This book is a collection of some major topics in neonatal neurology, delivering up-to-date data. The book covers several sections in a wide variety of aspects and interests. The topics include: VLBW infants and developmental follow up, kernicterus -- why is it persistent and can we make it go away, drugs and cerebral blood flow in the neonatal brain, neonatal EEG, neurological sequelae following mechanical ventilation, amplitude integrated EEG (aEEG), surgical treatment of post haemorrhagic hydrocephalus in the neonate, perinatal head trauma and neuro-trauma, and ethical approach to neonatal neurological issues.
As a result of technological improvements, neuroendoscopy is now used in the treatment of many more patients, enabling the performance of previously unavailable operations with low complication rates and rapid patient recovery. This book presents the distilled experience of world experts in this evolving field. Current applications in a wide variety of settings are explained in detail and likely future developments are identified. In addition, the available neuroendoscopic instruments are reviewed and the results of international trials and collaborative studies, presented. This book will fully acquaint the reader with the breadth and depth of available neuroendoscopy techniques and their impressive therapeutic potential. It should serve as the reference book on neuroendoscopy for the next 10 years.
Volume 21 of Recent Advances in Pediatrics is a compilation of reviews bringing trainees and physicians fully up to date with key developments in the field. Topics in this new volume include advances in neonatology, nutrition, gastroenterology and hepatology, psychiatry, endocrinology and critical care. Separate chapters are dedicated to vaccines and pharmacotherapy. Presented in an easy to follow format, Volume 21 follows a multidisciplinary approach. Each chapter finishes with a summary of key learning points and extensive references for further reading. Clinical photographs, illustrations and tables enhance learning. Key points New, updated volume presenting latest developments in paediatrics Multidisciplinary approach, easy to follow format Extensive references and key learning points summarised in each chapter Hot Topics Volume 20 published in 2011
Complement has long been regarded as a pivotal effector arm of the innate immune response, eliciting important immunoregulatory functions in the context of inflammation and also serving as a vital link between the innate and adaptive immune response. In the post-genomic era, our knowledge of the innate immune system is enriched by findings that point to novel functions that do not strictly correlate with immunological defense and surveillance, immune modulation or Inflammation. Several studies indicate that complement proteins exert functions that are either more complex than previously thought, or go well beyond the innate immune character of the system. The advent of high-throughput platforms for genome and proteome-wide profiling, together with the enormous amount of raw genetic information that has accumulated in the databases, have stirred new expectations in biomedical research. They have led complementologists to revisit established biological systems, such as the complement system, from a global and integrative perspective. Complement research is now faced with the challenge of trying to integrate isolated biochemical pathways into complex gene and protein regulatory circuits. In this respect, scientists from around the world convened at the Fourth Aegean Conferences Workshop on Complement Associated Diseases, Animal Models, and Therapeutics (June 10-15, 2007), to discuss recent advances in this fast evolving field. This volume represents a collection of topics on the “novel” functions of complement, patho-physiology, protein structures, design of complement inhibitors, and complement assays discussed during the conference.
Completely revised, the second edition of Key Topics in Neonatology provides a practical, systematic reference for all the major topics in neonatal medicine. Practical and easy to use, the book retains the same well-received format as the first edition, updates subject matter where significant recent developments have taken place, and widens the scope of the text by adding entirely new coverage. Distilling this large body of information into compact yet clear topics, the authors provide succinct reviews of issues that are often skimmed over in similar sized texts. This is the resource you will want on hand to solve the complex issues you face on a daily basis. New topics include: Abdominal Wall Defects Breast Feeding Cerebral Palsy Hearing Screening Hepatitis C Metabolic Acidosis Outcomes of Neonatal Intensive Care Updated topics include: Childbirth Complications and Fetal Outcome Chromosomal Abnormalities Chronic Lung Disease Complications of Mechanical Ventilation Congenital Malformations and Birth Defects Death of a Baby Extreme Prematurity Hepatitis B HIV/AIDS Immunisation Infants of Diabetic Mothers Jaundice Liver Disorders Maternal Drug Abuse Neonatal Screening for Inherited Disease Sedation and Analgesia on the Neonatal Intensive Care Unit Seizures Transfusion of Blood and Blood Products Transport of Sick Neonates, and more
Fetal and Neonatal Physiology, edited by Drs. Polin, Fox, and Abman, focuses on physiologic developments of the fetus and newborn and their impact on the clinical practice of neonatology. A must for practice, this 4th edition brings you the latest information on genetic therapy, intrauterine infections, brain protection and neuroimaging, and much more. You'll also have easy access to the complete contents and illustrations online at expertconsult.com.
Fetal and Neonatal Physiology, edited by Drs. Polin, Fox, and Abman, focuses on physiologic developments of the fetus and newborn and their impact on the clinical practice of neonatology. A must for practice, this 4th edition brings you the latest information on genetic therapy, intrauterine infections, brain protection and neuroimaging, and much more. Gain a comprehensive, state-of-the-art understanding of normal and abnormal physiology, and its relationship to disease in the fetus and newborn premature infant, from Dr. Richard Polin and other acknowledged worldwide leaders in the field. Understand the implications of fetal and neonatal physiology through chapters devoted to clinical correlation. Apply the latest insights on genetic therapy, intrauterine infections, brain protection and neuroimaging, and much more. Effectively manage the consequences of intrauterine infections with three new chapters covering intrauterine infection and preterm birth, intrauterine infection and brain injury, and intrauterine infection and chronic lung disease.
The 5th edition of this indispensable resource captures the latest insights in neonatal neurology in a totally engaging, readable manner. World authority Dr. Joseph Volpe has completely revised his masterwork from cover to cover, describing everything from the most up-to-the-minute discoveries in genetics through the latest advances in the diagnosis and management of neurologic disorders. He delivers all the clinical guidance you need to provide today's most effective care for neonates with neurological conditions. Provides comprehensive coverage of neonatal neurology, solely written by the field’s founding expert, Dr. Joseph Volpe - for a masterful, cohesive source of answers to any question that arises in your practice. Focuses on clinical evaluation and management, while also examining the many scientific and technological advances that are revolutionizing neonatal neurology. Organizes disease-focused chapters by affected body region for ease of reference. Offers comprehensive updates from cover to cover to reflect all of the latest scientific and clinical knowledge, from our most current understanding of the genetic underpinnings of neurologic disease, through the most recent neuroimaging advances . . . state-of-the-art guidelines for evaluation, diagnosis, and prognosis . . . and the newest management approaches for every type of neonatal neuropathology. Features a wealth of new, high-quality images that capture the many advances in neonatal neuroimaging, including numerous MR images.
A clear, engaging writing style, hundreds of full-color images, and new information throughout make Volpe’s Neurology of the Newborn, 6th Edition, an indispensable resource for those who provide care for neonates with neurological conditions. World authority Dr. Joseph Volpe, along with Dr. Terrie E. Inder and other distinguished editors, continue the unparalleled clarity and guidance you’ve come to expect from the leading reference in the field – keeping you up to date with today’s latest advances in diagnosis and management, as well as the many scientific and technological advances that are revolutionizing neonatal neurology. Features a brand new, full-color design with hundreds of new figures, tables, algorithms, and micrographs. Includes two entirely new chapters: Neurodevelopmental Follow-Up and Stroke in the Newborn; a new section on Neonatal Seizures; and an extensively expanded section on Hypoxic-Ischemia and Other Disorders. Showcases the experience and knowledge of a new editorial team, led by Dr. Joseph Volpe and Dr. Terrie E. Inder, Chair of the Department of Pediatric Newborn Medicine at Brigham and Women’s Hospital, all of whom bring a wealth of insight to this classic text. Offers comprehensive updates from cover to cover to reflect all of the latest information regarding the development of the neural tube; prosencephalic development; congenital hydrocephalus; cerebellar hemorrhage; neuromuscular disorders and genetic testing; and much more. Uses an improved organization to enhance navigation.