This book presents the cutting edge of developments in etiology, mechanisms of inflammation, disease manifestations and management of this common, crippling disease. Here is a new major volume on the subject of great importance in rheumatology - the first in-depth, multiauthor textbook on RAfor 15 years. Therapy for RA has traditionally been with non-steroid anti-inflammatory drugs, progressing to second-line drugs, but this has not been effective in preventing erosion of bone and symptoms. Rapid recent advances in knowledge have led to new concepts in the mechanisms of the disease andexciting new possibilities for treatment. This book deals with the scientific basis of the pathogenesis of rheumatoid arthritis which then goes on to form the basis of scientific discussion and the rationale for the treatment, both drug and non-drug, of the disease. The book describes the latestadvances in our understanding of this common, crippling disease and relates this knowledge to the application of a more rational therapeutic approach to its management The book covers all areas of importance to disease management including social and psychological aspects, genetic susceptibility,biological/immunological research, classic and other treatments (eg. physiotherapy, occupational therapy, complementary therapy, diet and patient education), management of pain, health economics and disease management strategies. This book is a 'must' for all rheumatologists and anyone working inthe field.
This authoritative clinical reference provides comprehensive coverage of all aspects of rheumatoid arthritis. The basics of rheumatoid arthritis are thoroughly covered in order to provide a firm foundation for the main focus of the text: therapy and clinical management of the disease. Practitioners will find detailed information on both pharmacologic and nonpharmacologic courses of management, with special emphasis on the management of pain. More than 100 full-color illustrations provide clear visual support for the concepts in the text. Online references in each chapter, as well as an entire chapter on Web-based information resources, keep this book on the cutting edge of this rapidly evolving field.
Rheumatoid arthritis is a common but often debilitating disorder. Given the intricate and challenging nature of treating rheumatoid arthritis, it is imperative to educate physicians on the disease's initial symptoms and complications, as well as to provide accurate and up-to-date information regarding effective treatment. Designed to help eradicate misconceptions concerning rheumatoid arthritis and its treatment, this concise volume helps clinicians to understand and then effectively diagnose and treat patients with the condition. Part of the Oxford American Rheumatology Library, this concise guide serves as a practical, user-friendly reference for rheumatologists and other healthcare professionals. The book provides an overview of rheumatoid arthritis, including its epidemiology, symptoms, signs, and pathophysiology. Using the most current information available, the author evaluates both traditional and innovative treatment methods. A thorough glossary defines key terms and the appendix includes related resource information - associations, journals and doctors/researchers - all devoted to the study and treatment of rheumatoid arthritis.
Rheumatoid Arthritis - Other Perspectives towards Better Practice sheds light on the disease process of rheumatoid arthritis as well as the disease’s related comorbidities. Chapters cover such topics as immune-pathogenic theories, classification criteria, available composite measures of disease assessment, and latest available therapeutic approaches.
The purpose of this book is to provide up-to-date, interesting, and thought-provoking perspectives on various aspects of research into current and potential treatments for rheumatoid arthritis (RA). This book features 17 chapters, with contributions from numerous countries (e.g. UK, USA, Canada, Japan, Sweden, Turkey, Bosnia and Herzegovina, Slovakia), including chapters from internationally recognized leaders in rheumatology research. It is anticipated that Rheumatoid Arthritis - Treatment will provide both a useful reference and source of potential areas of investigation for research scientists working in the field of RA and other inflammatory arthropathies.
Many advances have occurred in the last 5 years especially in understanding genetic susceptibility factors, the role of immune response in chronic arthritis and the relationship between cellular processes that underlie inflammation and tissue damage. All these are dealt with in depth in the individual contributions. Genetics studies included illustrate how studies of HLA genes and genes controlling the autoantibody repertoire may be involved. Environmental factors are believed to be important and studies both in humans and in experimental models on the role of viral and bacterial agents are covered. The fascinating relationship between microbes, dysregulated immune responses and oncogenes are also examined. Since autoimmunity is the key aspect of the immunological response in rheumatoid arthritis, the role of antigens is re-examined as is the part played by immune T and B cells. New areas of clinical application of basic science is well presented in this book, forexample, in examining how markers of cartilage destruction may become important in monitoring disease activity. A chapter reviewing possible future novel therapies is included.
Rheumatoid arthritis (RA) is a chronic autoimmune disease generating joint pain and damage in which inflammation plays a major role. RA joints are inflamed and stiff. Symptoms include joint swelling and warmth causing fatigue affecting life’s health-related quality. Still, there are many other medical conditions that can also be associated with your symptoms and signs. This book is not a substitute for a diagnosis from a healthcare provider. Yet, understanding your symptoms and signs and educating yourself about health conditions is important and can contribute to having the healthiest possible life. Herein, Professor Hechmi Toumi offers an edited volume with detailed new information on RA pathogenesis and explains both approaches and treatment options: recent clinical research and traditional methods.
Atlas of Rheumatoid Arthritis is a high-quality educational initiative, written by leaders in the field of rheumatology, containing a collection of approximately 150 relevant images, with extended descriptive captions and a comprehensive bibliography. The Atlas of Rheumatoid Arthritis will provide clinicians with a visual guide to rheumatoid arthritis, focusing on assessment, diagnosis and treatment, including newer research into the signalling pathways involved in the pathogenesis of RA, before focusing on the treatment of RA. Rheumatoid arthritis (RA) is the most common and most serious of the inflammatory arthritic disorders, and it dominates clinical rheumatological practice. Effective, early treatment is vital as this can slow the course of the disease and reduce joint damage. RA is usually treated using disease-modifying anti-rheumatic drugs (DMARDs), most commonly methotrexate. The newest treatments target the disease-causing immune elements specifically and directly.
This brand new textbook of rheumatoid arthritis (RA) is an important addition to the Oxford Textbooks in Rheumatology series, and provides a comprehensive overview of both the scientific and clinical aspects of the disease. Divided into eight sections - from the history, diagnosis, and epidemiology of the disease, through the pathogenesis, clinical presentation, and assessment to treatments and management strategies, both drug- and non-drug based - each chapter is written by leading clinicians and scientists in the field to deliver a contemporary view of RA. During the past two decades there have been revolutionary changes in the understanding and management of rheumatoid arthritis, in particular the development of biological treatments. This has had wide-ranging effects on almost all aspects of treatment, from effectiveness and intensity to the nature and the cost. Providing a comprehensive account of the modern ideas about the disease, the Oxford Textbook of Rheumatoid Arthritis is a key new addition to the literature, with each chapter providing a detailed background, key recent advances, and areas of doubt and future developments. Featuring over 170 photographs, radiological images, and clinical charts to aid both diagnosis and illustrate the rationale behind key scientific studies, this new title will prove an indispensable resource for specialist rheumatologists, trainees in rheumatology, and other members of the multi-disciplinary team.
